diff --git a/Modules/_ctypes/libffi/fficonfig.py.in b/Modules/_ctypes/libffi/fficonfig.py.in
index f5f3810b0d9..10293273588 100644
--- a/Modules/_ctypes/libffi/fficonfig.py.in
+++ b/Modules/_ctypes/libffi/fficonfig.py.in
@@ -25,7 +25,7 @@ ffi_platforms = {
     'SH64': ['src/sh64/sysv.S', 'src/sh64/ffi.c'],
     'PA': ['src/pa/linux.S', 'src/pa/ffi.c'],
     'PA_LINUX': ['src/pa/linux.S', 'src/pa/ffi.c'],
-    'PA_HPUX': ['src/pa/hpux32.s', 'src/pa/ffi.c'],
+    'PA_HPUX': ['src/pa/hpux32.S', 'src/pa/ffi.c'],
 }
 
 ffi_srcdir = '@srcdir@'
diff --git a/setup.py b/setup.py
index 6173ab24a9a..136e0a1add8 100644
--- a/setup.py
+++ b/setup.py
@@ -1607,7 +1607,7 @@ class PyBuildExt(build_ext):
             # finding some -z option for the Sun compiler.
             extra_link_args.append('-mimpure-text')
 
-        elif sys.platform.startswith('hpux'):
+        elif sys.platform.startswith('hp-ux'):
             extra_link_args.append('-fPIC')
 
         ext = Extension('_ctypes',