diff --git a/Modules/_ctypes/libffi/fficonfig.py.in b/Modules/_ctypes/libffi/fficonfig.py.in
index 09c13db38d4..f5f3810b0d9 100644
--- a/Modules/_ctypes/libffi/fficonfig.py.in
+++ b/Modules/_ctypes/libffi/fficonfig.py.in
@@ -25,6 +25,7 @@ ffi_platforms = {
     'SH64': ['src/sh64/sysv.S', 'src/sh64/ffi.c'],
     'PA': ['src/pa/linux.S', 'src/pa/ffi.c'],
     'PA_LINUX': ['src/pa/linux.S', 'src/pa/ffi.c'],
+    'PA_HPUX': ['src/pa/hpux32.s', 'src/pa/ffi.c'],
 }
 
 ffi_srcdir = '@srcdir@'
diff --git a/setup.py b/setup.py
index 34035edd32c..4663cece8c1 100644
--- a/setup.py
+++ b/setup.py
@@ -1580,6 +1580,9 @@ class PyBuildExt(build_ext):
             # finding some -z option for the Sun compiler.
             extra_link_args.append('-mimpure-text')
 
+        elif sys.platform.startswith('hpux'):
+            extra_link_args.append('-fPIC')
+
         ext = Extension('_ctypes',
                         include_dirs=include_dirs,
                         extra_compile_args=extra_compile_args,