diff --git a/Tools/px_uploader.py b/Tools/px_uploader.py
index 8b872ce738..e0bcff2e70 100755
--- a/Tools/px_uploader.py
+++ b/Tools/px_uploader.py
@@ -546,7 +546,12 @@ class uploader(object):
         if self.baudrate_flightstack_idx >= len(self.baudrate_flightstack):
             return False
 
-        self.port.baudrate = self.baudrate_flightstack[self.baudrate_flightstack_idx]
+        try:
+            self.port.baudrate = self.baudrate_flightstack[self.baudrate_flightstack_idx]
+        except serial.SerialException:
+            # Sometimes _configure_port fails
+            time.sleep(0.04)
+            pass
 
         return True