diff --git a/Doc/c-api/module.rst b/Doc/c-api/module.rst
index 3ea7aeb55d0..8a15a5ea83e 100644
--- a/Doc/c-api/module.rst
+++ b/Doc/c-api/module.rst
@@ -549,6 +549,14 @@ state:
    Note that ``Py_XDECREF()`` should be used instead of ``Py_DECREF()`` in
    this case, since *obj* can be ``NULL``.
 
+   The number of different *name* strings passed to this function
+   should be kept small, usually by only using statically allocated strings
+   as *name*.
+   For names that aren't known at compile time, prefer calling
+   :c:func:`PyUnicode_FromString` and :c:func:`PyObject_SetAttr` directly.
+   For more details, see :c:func:`PyUnicode_InternFromString`, which may be
+   used internally to create a key object.
+
    .. versionadded:: 3.10
 
 
@@ -610,6 +618,9 @@ state:
    used from the module's initialization function.
    Return ``-1`` with an exception set on error, ``0`` on success.
 
+   This is a convenience function that calls :c:func:`PyLong_FromLong` and
+   :c:func:`PyModule_AddObjectRef`; see their documentation for details.
+
 
 .. c:function:: int PyModule_AddStringConstant(PyObject *module, const char *name, const char *value)
 
@@ -618,6 +629,10 @@ state:
    ``NULL``-terminated.
    Return ``-1`` with an exception set on error, ``0`` on success.
 
+   This is a convenience function that calls
+   :c:func:`PyUnicode_InternFromString` and :c:func:`PyModule_AddObjectRef`;
+   see their documentation for details.
+
 
 .. c:macro:: PyModule_AddIntMacro(module, macro)
 
diff --git a/Doc/c-api/object.rst b/Doc/c-api/object.rst
index 2103a64d8ff..1c28f30321b 100644
--- a/Doc/c-api/object.rst
+++ b/Doc/c-api/object.rst
@@ -206,6 +206,13 @@ Object Protocol
    If *v* is ``NULL``, the attribute is deleted, but this feature is
    deprecated in favour of using :c:func:`PyObject_DelAttrString`.
 
+   The number of different attribute names passed to this function
+   should be kept small, usually by using a statically allocated string
+   as *attr_name*.
+   For attribute names that aren't known at compile time, prefer calling
+   :c:func:`PyUnicode_FromString` and :c:func:`PyObject_SetAttr` directly.
+   For more details, see :c:func:`PyUnicode_InternFromString`, which may be
+   used internally to create a key object.
 
 .. c:function:: int PyObject_GenericSetAttr(PyObject *o, PyObject *name, PyObject *value)
 
@@ -231,6 +238,14 @@ Object Protocol
    specified as a :c:expr:`const char*` UTF-8 encoded bytes string,
    rather than a :c:expr:`PyObject*`.
 
+   The number of different attribute names passed to this function
+   should be kept small, usually by using a statically allocated string
+   as *attr_name*.
+   For attribute names that aren't known at compile time, prefer calling
+   :c:func:`PyUnicode_FromString` and :c:func:`PyObject_DelAttr` directly.
+   For more details, see :c:func:`PyUnicode_InternFromString`, which may be
+   used internally to create a key object for lookup.
+
 
 .. c:function:: PyObject* PyObject_GenericGetDict(PyObject *o, void *context)
 
diff --git a/Doc/c-api/unicode.rst b/Doc/c-api/unicode.rst
index 246cf47df62..958fafd47ac 100644
--- a/Doc/c-api/unicode.rst
+++ b/Doc/c-api/unicode.rst
@@ -1490,18 +1490,43 @@ They all return ``NULL`` or ``-1`` if an exception occurs.
    existing interned string that is the same as :c:expr:`*p_unicode`, it sets :c:expr:`*p_unicode` to
    it (releasing the reference to the old string object and creating a new
    :term:`strong reference` to the interned string object), otherwise it leaves
-   :c:expr:`*p_unicode` alone and interns it (creating a new :term:`strong reference`).
+   :c:expr:`*p_unicode` alone and interns it.
+
    (Clarification: even though there is a lot of talk about references, think
-   of this function as reference-neutral; you own the object after the call
-   if and only if you owned it before the call.)
+   of this function as reference-neutral. You must own the object you pass in;
+   after the call you no longer own the passed-in reference, but you newly own
+   the result.)
+
+   This function never raises an exception.
+   On error, it leaves its argument unchanged without interning it.
+
+   Instances of subclasses of :py:class:`str` may not be interned, that is,
+   :c:expr:`PyUnicode_CheckExact(*p_unicode)` must be true. If it is not,
+   then -- as with any other error -- the argument is left unchanged.
+
+   Note that interned strings are not “immortal”.
+   You must keep a reference to the result to benefit from interning.
 
 
 .. c:function:: PyObject* PyUnicode_InternFromString(const char *str)
 
    A combination of :c:func:`PyUnicode_FromString` and
-   :c:func:`PyUnicode_InternInPlace`, returning either a new Unicode string
-   object that has been interned, or a new ("owned") reference to an earlier
-   interned string object with the same value.
+   :c:func:`PyUnicode_InternInPlace`, meant for statically allocated strings.
+
+   Return a new ("owned") reference to either a new Unicode string object
+   that has been interned, or an earlier interned string object with the
+   same value.
+
+   Python may keep a reference to the result, or make it :term:`immortal`,
+   preventing it from being garbage-collected promptly.
+   For interning an unbounded number of different strings, such as ones coming
+   from user input, prefer calling :c:func:`PyUnicode_FromString` and
+   :c:func:`PyUnicode_InternInPlace` directly.
+
+   .. impl-detail::
+
+      Strings interned this way are made :term:`immortal`.
+
 
 PyUnicodeWriter
 ^^^^^^^^^^^^^^^
diff --git a/Misc/NEWS.d/next/C API/2024-07-04-15-41-10.gh-issue-113993.cLSiWV.rst b/Misc/NEWS.d/next/C API/2024-07-04-15-41-10.gh-issue-113993.cLSiWV.rst
new file mode 100644
index 00000000000..9b7f2082065
--- /dev/null
+++ b/Misc/NEWS.d/next/C API/2024-07-04-15-41-10.gh-issue-113993.cLSiWV.rst	
@@ -0,0 +1,12 @@
+:c:func:`PyUnicode_InternInPlace` no longer prevents its argument from being
+garbage collected.
+
+Several functions that take ``char *`` are now
+documented as possibly preventing string objects from being garbage
+collected; refer to their documentation for details:
+:c:func:`PyUnicode_InternFromString`,
+:c:func:`PyDict_SetItemString`,
+:c:func:`PyObject_SetAttrString`,
+:c:func:`PyObject_DelAttrString`,
+:c:func:`PyUnicode_InternFromString`,
+and ``PyModule_Add*`` convenience functions.
diff --git a/Modules/_ctypes/_ctypes.c b/Modules/_ctypes/_ctypes.c
index db58f33511c..b55102639c6 100644
--- a/Modules/_ctypes/_ctypes.c
+++ b/Modules/_ctypes/_ctypes.c
@@ -2303,9 +2303,14 @@ PyCSimpleType_init(PyObject *self, PyObject *args, PyObject *kwds)
             if (!meth) {
                 return -1;
             }
-            x = PyDict_SetItemString(((PyTypeObject*)self)->tp_dict,
-                                     ml->ml_name,
-                                     meth);
+            PyObject *name = PyUnicode_FromString(ml->ml_name);
+            if (name == NULL) {
+                Py_DECREF(meth);
+                return -1;
+            }
+            PyUnicode_InternInPlace(&name);
+            x = PyDict_SetItem(((PyTypeObject*)self)->tp_dict, name, meth);
+            Py_DECREF(name);
             Py_DECREF(meth);
             if (x == -1) {
                 return -1;
diff --git a/Objects/unicodeobject.c b/Objects/unicodeobject.c
index c2fb135ed68..408d74fb3af 100644
--- a/Objects/unicodeobject.c
+++ b/Objects/unicodeobject.c
@@ -15584,7 +15584,7 @@ void
 PyUnicode_InternInPlace(PyObject **p)
 {
     PyInterpreterState *interp = _PyInterpreterState_GET();
-    _PyUnicode_InternImmortal(interp, p);
+    _PyUnicode_InternMortal(interp, p);
 }
 
 // Public-looking name kept for the stable ABI; user should not call this: