diff --git a/Lib/ctypes/test/test_functions.py b/Lib/ctypes/test/test_functions.py
index c5456ba107a..f9e92e1cc6b 100644
--- a/Lib/ctypes/test/test_functions.py
+++ b/Lib/ctypes/test/test_functions.py
@@ -35,34 +35,24 @@ class FunctionTestCase(unittest.TestCase):
         # wasn't checked, and it even crashed Python.
         # Found by Greg Chapman.
 
-        try:
+        with self.assertRaises(TypeError):
             class X(object, Array):
                 _length_ = 5
                 _type_ = "i"
-        except TypeError:
-            pass
-
 
         from _ctypes import _Pointer
-        try:
+        with self.assertRaises(TypeError):
             class X(object, _Pointer):
                 pass
-        except TypeError:
-            pass
 
         from _ctypes import _SimpleCData
-        try:
+        with self.assertRaises(TypeError):
             class X(object, _SimpleCData):
                 _type_ = "i"
-        except TypeError:
-            pass
 
-        try:
+        with self.assertRaises(TypeError):
             class X(object, Structure):
                 _fields_ = []
-        except TypeError:
-            pass
-
 
     @need_symbol('c_wchar')
     def test_wchar_parm(self):
diff --git a/Misc/NEWS.d/next/Tests/2021-11-23-12-36-21.bpo-45878.eOs_Mp.rst b/Misc/NEWS.d/next/Tests/2021-11-23-12-36-21.bpo-45878.eOs_Mp.rst
new file mode 100644
index 00000000000..fca90ef4698
--- /dev/null
+++ b/Misc/NEWS.d/next/Tests/2021-11-23-12-36-21.bpo-45878.eOs_Mp.rst
@@ -0,0 +1,2 @@
+Test ``Lib/ctypes/test/test_functions.py::test_mro`` now uses
+``self.assertRaises`` instead of ``try/except``.