diff --git a/Lib/test/test_isinstance.py b/Lib/test/test_isinstance.py
index 91e79c29548..109c3f84a5c 100644
--- a/Lib/test/test_isinstance.py
+++ b/Lib/test/test_isinstance.py
@@ -303,6 +303,16 @@ class TestIsInstanceIsSubclass(unittest.TestCase):
 
         self.assertEqual(True, issubclass(B(), int))
 
+    def test_infinite_recursion_in_bases(self):
+        class X:
+            @property
+            def __bases__(self):
+                return self.__bases__
+
+        self.assertRaises(RecursionError, issubclass, X(), int)
+        self.assertRaises(RecursionError, issubclass, int, X())
+        self.assertRaises(RecursionError, isinstance, 1, X())
+
 
 def blowstack(fxn, arg, compare_to):
     # Make sure that calling isinstance with a deeply nested tuple for its
diff --git a/Misc/NEWS.d/next/Core and Builtins/2020-10-04-10-55-12.bpo-41909.BqHPcm.rst b/Misc/NEWS.d/next/Core and Builtins/2020-10-04-10-55-12.bpo-41909.BqHPcm.rst
new file mode 100644
index 00000000000..388cfea065e
--- /dev/null
+++ b/Misc/NEWS.d/next/Core and Builtins/2020-10-04-10-55-12.bpo-41909.BqHPcm.rst	
@@ -0,0 +1,2 @@
+Fixed stack overflow in :func:`issubclass` and :func:`isinstance` when
+getting the ``__bases__`` attribute leads to infinite recursion.
diff --git a/Objects/abstract.c b/Objects/abstract.c
index c471f184f6c..c30fb4eb6a6 100644
--- a/Objects/abstract.c
+++ b/Objects/abstract.c
@@ -2336,9 +2336,7 @@ abstract_get_bases(PyObject *cls)
     _Py_IDENTIFIER(__bases__);
     PyObject *bases;
 
-    Py_ALLOW_RECURSION
     (void)_PyObject_LookupAttrId(cls, &PyId___bases__, &bases);
-    Py_END_ALLOW_RECURSION
     if (bases != NULL && !PyTuple_Check(bases)) {
         Py_DECREF(bases);
         return NULL;
diff --git a/Objects/unicodeobject.c b/Objects/unicodeobject.c
index cf72238a8d0..6ae06a508c6 100644
--- a/Objects/unicodeobject.c
+++ b/Objects/unicodeobject.c
@@ -15734,9 +15734,7 @@ PyUnicode_InternInPlace(PyObject **p)
     }
 
     PyObject *t;
-    Py_ALLOW_RECURSION
     t = PyDict_SetDefault(interned, s, s);
-    Py_END_ALLOW_RECURSION
 
     if (t == NULL) {
         PyErr_Clear();