diff --git a/Lib/test/test_gdb.py b/Lib/test/test_gdb.py
index 98b36d6cd04..22a8cf3c25f 100644
--- a/Lib/test/test_gdb.py
+++ b/Lib/test/test_gdb.py
@@ -145,7 +145,8 @@ class DebuggerTests(unittest.TestCase):
     def get_stack_trace(self, source=None, script=None,
                         breakpoint=BREAKPOINT_FN,
                         cmds_after_breakpoint=None,
-                        import_site=False):
+                        import_site=False,
+                        ignore_stderr=False):
         '''
         Run 'python -c SOURCE' under gdb with a breakpoint.
 
@@ -224,8 +225,9 @@ class DebuggerTests(unittest.TestCase):
         # Use "args" to invoke gdb, capturing stdout, stderr:
         out, err = run_gdb(*args, PYTHONHASHSEED=PYTHONHASHSEED)
 
-        for line in err.splitlines():
-            print(line, file=sys.stderr)
+        if not ignore_stderr:
+            for line in err.splitlines():
+                print(line, file=sys.stderr)
 
         # bpo-34007: Sometimes some versions of the shared libraries that
         # are part of the traceback are compiled in optimised mode and the
@@ -909,6 +911,9 @@ id(42)
                         cmd,
                         breakpoint=func_name,
                         cmds_after_breakpoint=['bt', 'py-bt'],
+                        # bpo-45207: Ignore 'Function "meth_varargs" not
+                        # defined.' message in stderr.
+                        ignore_stderr=True,
                     )
                     self.assertIn(f'<built-in method {func_name}', gdb_output)
 
@@ -917,6 +922,9 @@ id(42)
                         cmd,
                         breakpoint=func_name,
                         cmds_after_breakpoint=['py-bt-full'],
+                        # bpo-45207: Ignore 'Function "meth_varargs" not
+                        # defined.' message in stderr.
+                        ignore_stderr=True,
                     )
                     self.assertIn(
                         f'#{expected_frame} <built-in method {func_name}',