diff --git a/Lib/test/test_wsgiref.py b/Lib/test/test_wsgiref.py
index 8051b4a0813..b8cf6351290 100644
--- a/Lib/test/test_wsgiref.py
+++ b/Lib/test/test_wsgiref.py
@@ -342,6 +342,10 @@ class UtilityTests(TestCase):
         self.checkReqURI("http://127.0.0.1/sp%C3%A4m", SCRIPT_NAME="/späm")
         self.checkReqURI("http://127.0.0.1/spammity/spam",
             SCRIPT_NAME="/spammity", PATH_INFO="/spam")
+        self.checkReqURI("http://127.0.0.1/spammity/spam;ham",
+            SCRIPT_NAME="/spammity", PATH_INFO="/spam;ham")
+        self.checkReqURI("http://127.0.0.1/spammity/spam;cookie=1234,5678",
+            SCRIPT_NAME="/spammity", PATH_INFO="/spam;cookie=1234,5678")
         self.checkReqURI("http://127.0.0.1/spammity/spam?say=ni",
             SCRIPT_NAME="/spammity", PATH_INFO="/spam",QUERY_STRING="say=ni")
         self.checkReqURI("http://127.0.0.1/spammity/spam", 0,
diff --git a/Lib/wsgiref/util.py b/Lib/wsgiref/util.py
index ae982f05911..1f1e6cce179 100644
--- a/Lib/wsgiref/util.py
+++ b/Lib/wsgiref/util.py
@@ -64,7 +64,7 @@ def request_uri(environ, include_query=True):
     """Return the full request URI, optionally including the query string"""
     url = application_uri(environ)
     from urllib.parse import quote
-    path_info = quote(environ.get('PATH_INFO',''))
+    path_info = quote(environ.get('PATH_INFO',''),safe='/;=,')
     if not environ.get('SCRIPT_NAME'):
         url += path_info[1:]
     else:
diff --git a/Misc/NEWS b/Misc/NEWS
index 530fcc79e27..b4e4cf96f88 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -20,6 +20,11 @@ Core and Builtins
 Library
 -------
 
+- Issue 10753 - Characters ';','=' and ',' in the PATH_INFO environment
+  variable won't be quoted when the URI is constructed by the wsgiref.util 's
+  request_uri method. According to RFC 3986, these characters can be a part of
+  params in PATH component of URI and need not be quoted.
+
 - Issue 10738: Fix webbrowser.Opera.raise_opts
 
 - Issue 9824: SimpleCookie now encodes , and ; in values to cater to how