diff --git a/Lib/test/test_doctest.py b/Lib/test/test_doctest.py
index bff20f9cac9..6a5013f5b8a 100644
--- a/Lib/test/test_doctest.py
+++ b/Lib/test/test_doctest.py
@@ -3039,10 +3039,11 @@ Invalid file name:
     ...         '-m', 'doctest', 'nosuchfile')
     >>> rc, out
     (1, b'')
+    >>> # The exact error message changes depending on the platform.
     >>> print(normalize(err))                    # doctest: +ELLIPSIS
     Traceback (most recent call last):
       ...
-    FileNotFoundError: [Errno ...] No such file or directory: 'nosuchfile'
+    FileNotFoundError: [Errno ...] ...nosuchfile...
 
 Invalid doctest option:
 
diff --git a/Misc/NEWS.d/next/Tests/2020-11-20-15-07-18.bpo-31904.EBJXjJ.rst b/Misc/NEWS.d/next/Tests/2020-11-20-15-07-18.bpo-31904.EBJXjJ.rst
new file mode 100644
index 00000000000..e5e66ceea44
--- /dev/null
+++ b/Misc/NEWS.d/next/Tests/2020-11-20-15-07-18.bpo-31904.EBJXjJ.rst
@@ -0,0 +1 @@
+Fix test_doctest.py failures for VxWorks.