diff --git a/Misc/NEWS.d/next/Core and Builtins/2018-06-05-15-49-02.bpo-30167.e956hA.rst b/Misc/NEWS.d/next/Core and Builtins/2018-06-05-15-49-02.bpo-30167.e956hA.rst
new file mode 100644
index 00000000000..41bdec899b7
--- /dev/null
+++ b/Misc/NEWS.d/next/Core and Builtins/2018-06-05-15-49-02.bpo-30167.e956hA.rst	
@@ -0,0 +1,2 @@
+``PyRun_SimpleFileExFlags`` removes ``__cached__`` from module in addition
+to ``__file__``.
diff --git a/Python/pythonrun.c b/Python/pythonrun.c
index 2d5dc88c5c7..9b6371d9c0d 100644
--- a/Python/pythonrun.c
+++ b/Python/pythonrun.c
@@ -434,8 +434,14 @@ PyRun_SimpleFileExFlags(FILE *fp, const char *filename, int closeit,
     Py_DECREF(v);
     ret = 0;
   done:
-    if (set_file_name && PyDict_DelItemString(d, "__file__"))
-        PyErr_Clear();
+    if (set_file_name) {
+        if (PyDict_DelItemString(d, "__file__")) {
+            PyErr_Clear();
+        }
+        if (PyDict_DelItemString(d, "__cached__")) {
+            PyErr_Clear();
+        }
+    }
     Py_XDECREF(m);
     return ret;
 }