diff --git a/Lib/pickletools.py b/Lib/pickletools.py
index 6b86723a4c0..cf5df4158a0 100644
--- a/Lib/pickletools.py
+++ b/Lib/pickletools.py
@@ -1898,7 +1898,7 @@ opcodes = [
       arg=None,
       stack_before=[pyunicode, pyunicode],
       stack_after=[anyobject],
-      proto=0,
+      proto=4,
       doc="""Push a global object (module.attr) on the stack.
       """),
 
diff --git a/Misc/NEWS b/Misc/NEWS
index b5a70e56409..23b6ebcc2a1 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -96,6 +96,9 @@ Core and Builtins
 Library
 -------
 
+- Issue #25380: Fixed protocol for the STACK_GLOBAL opcode in
+  pickletools.opcodes.
+
 - Issue #23972: Updates asyncio datagram create method allowing reuseport
   and reuseaddr socket options to be set prior to binding the socket.
   Mirroring the existing asyncio create_server method the reuseaddr option