diff --git a/Misc/NEWS b/Misc/NEWS
index 26a3f87aa28..406d5f36369 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -156,6 +156,8 @@ Build
 
 - Patch #1429775: Link extension modules with the shared libpython.
 
+- Fixed a libffi build problem on MIPS systems.
+
 C API
 -----
 
diff --git a/Modules/_ctypes/libffi/configure b/Modules/_ctypes/libffi/configure
index c1e5cd402ec..27abbecbb3e 100755
--- a/Modules/_ctypes/libffi/configure
+++ b/Modules/_ctypes/libffi/configure
@@ -310,7 +310,7 @@ ac_includes_default="\
 # include <unistd.h>
 #endif"
 
-ac_subst_vars='SHELL PATH_SEPARATOR PACKAGE_NAME PACKAGE_TARNAME PACKAGE_VERSION PACKAGE_STRING PACKAGE_BUGREPORT exec_prefix prefix program_transform_name bindir sbindir libexecdir datadir sysconfdir sharedstatedir localstatedir libdir includedir oldincludedir infodir mandir build_alias host_alias target_alias DEFS ECHO_C ECHO_N ECHO_T LIBS build build_cpu build_vendor build_os host host_cpu host_vendor host_os target target_cpu target_vendor target_os CC ac_ct_CC EXEEXT OBJEXT CFLAGS CPP CPPFLAGS EGREP ALLOCA HAVE_LONG_DOUBLE TARGET TARGETDIR LIBOBJS LTLIBOBJS'
+ac_subst_vars='SHELL PATH_SEPARATOR PACKAGE_NAME PACKAGE_TARNAME PACKAGE_VERSION PACKAGE_STRING PACKAGE_BUGREPORT exec_prefix prefix program_transform_name bindir sbindir libexecdir datadir sysconfdir sharedstatedir localstatedir libdir includedir oldincludedir infodir mandir build_alias host_alias target_alias DEFS ECHO_C ECHO_N ECHO_T LIBS build build_cpu build_vendor build_os host host_cpu host_vendor host_os target target_cpu target_vendor target_os CC ac_ct_CC EXEEXT OBJEXT CFLAGS CPP CPPFLAGS EGREP ALLOCA HAVE_LONG_DOUBLE TARGET TARGETDIR MKTARGET LIBOBJS LTLIBOBJS'
 ac_subst_files=''
 
 # Initialize some variables set by options.
@@ -3534,6 +3534,8 @@ echo "$as_me: error: \"libffi has not been ported to $host.\"" >&2;}
    { (exit 1); exit 1; }; }
 fi
 
+MKTARGET=$TARGET
+
 case x$TARGET in
   xMIPS*) TARGET=MIPS ;;
   *) ;;
@@ -5457,6 +5459,7 @@ fi
 
 
 
+
 cat >>confdefs.h <<\_ACEOF
 #define FFI_NO_RAW_API 1
 _ACEOF
@@ -6129,6 +6132,7 @@ s,@ALLOCA@,$ALLOCA,;t t
 s,@HAVE_LONG_DOUBLE@,$HAVE_LONG_DOUBLE,;t t
 s,@TARGET@,$TARGET,;t t
 s,@TARGETDIR@,$TARGETDIR,;t t
+s,@MKTARGET@,$MKTARGET,;t t
 s,@LIBOBJS@,$LIBOBJS,;t t
 s,@LTLIBOBJS@,$LTLIBOBJS,;t t
 CEOF
diff --git a/Modules/_ctypes/libffi/configure.ac b/Modules/_ctypes/libffi/configure.ac
index c7f05d65246..6dafe35fe86 100644
--- a/Modules/_ctypes/libffi/configure.ac
+++ b/Modules/_ctypes/libffi/configure.ac
@@ -70,6 +70,12 @@ if test $TARGETDIR = unknown; then
   AC_MSG_ERROR(["libffi has not been ported to $host."])
 fi
 
+dnl  libffi changes TARGET for MIPS to define a such macro in the header
+dnl  while MIPS_IRIX or MIPS_LINUX is separatedly used to decide which
+dnl  files will be compiled.  So, we need to keep the original decision
+dnl  of TARGET to use in fficonfig.py.in.
+MKTARGET=$TARGET
+
 case x$TARGET in
   xMIPS*) TARGET=MIPS ;;
   *) ;;
@@ -183,6 +189,7 @@ AH_BOTTOM([
 
 AC_SUBST(TARGET)
 AC_SUBST(TARGETDIR)
+AC_SUBST(MKTARGET)
 
 AC_SUBST(SHELL)
 
diff --git a/Modules/_ctypes/libffi/fficonfig.py.in b/Modules/_ctypes/libffi/fficonfig.py.in
index 5e53c6dd48b..89f79693b33 100644
--- a/Modules/_ctypes/libffi/fficonfig.py.in
+++ b/Modules/_ctypes/libffi/fficonfig.py.in
@@ -27,7 +27,7 @@ ffi_platforms = {
 }
 
 ffi_srcdir = '@srcdir@'
-ffi_sources += ffi_platforms['@TARGET@']
+ffi_sources += ffi_platforms['@MKTARGET@']
 ffi_sources = [os.path.join('@srcdir@', f) for f in ffi_sources]
 
 ffi_cflags = '@CFLAGS@'