diff --git a/Makefile.pre.in b/Makefile.pre.in
index 6dec272ab82..1b6965592e8 100644
--- a/Makefile.pre.in
+++ b/Makefile.pre.in
@@ -27,6 +27,8 @@ MODLIBS=        _MODLIBS_
 VERSION=	@VERSION@
 srcdir=		@srcdir@
 VPATH=		@srcdir@
+BUILDDIR=	@BUILDDIR@
+
 
 CC=		@CC@
 CXX=		@CXX@
@@ -66,6 +68,7 @@ MAKESETUP=      $(srcdir)/Modules/makesetup
 # Compiler options
 OPT=		@OPT@
 BASECFLAGS=	@BASECFLAGS@
+BASECPPFLAGS=	@BASECPPFLAGS@
 CONFIGURE_CFLAGS=	@CFLAGS@
 CONFIGURE_CPPFLAGS=	@CPPFLAGS@
 CONFIGURE_LDFLAGS=	@LDFLAGS@
@@ -76,7 +79,7 @@ PY_CFLAGS=	$(BASECFLAGS) $(OPT) $(CONFIGURE_CFLAGS) $(CFLAGS) $(EXTRA_CFLAGS)
 # Both CPPFLAGS and LDFLAGS need to contain the shell's value for setup.py to
 # be able to build extension modules using the directories specified in the
 # environment variables
-PY_CPPFLAGS=	-I. -IInclude -I$(srcdir)/Include $(CONFIGURE_CPPFLAGS) $(CPPFLAGS)
+PY_CPPFLAGS=	$(BASECPPFLAGS) -I. -IInclude -I$(srcdir)/Include $(CONFIGURE_CPPFLAGS) $(CPPFLAGS)
 PY_LDFLAGS=	$(CONFIGURE_LDFLAGS) $(LDFLAGS)
 NO_AS_NEEDED=	@NO_AS_NEEDED@
 LDLAST=		@LDLAST@
@@ -282,7 +285,7 @@ ASDLGEN=	@DISABLE_ASDLGEN@ $(srcdir)/Parser/asdl_c.py
 # Python
 
 OPCODETARGETS_H= \
-		$(srcdir)/Python/opcode_targets.h
+		Python/opcode_targets.h
 
 OPCODETARGETGEN= \
 		$(srcdir)/Python/makeopcodetargets.py
@@ -663,9 +666,9 @@ Python/formatter_unicode.o: $(srcdir)/Python/formatter_unicode.c \
 				$(BYTESTR_DEPS) \
 				$(srcdir)/Objects/stringlib/formatter.h
 
-Objects/typeobject.o: $(srcdir)/Objects/typeslots.inc
-$(srcdir)/Objects/typeslots.inc: $(srcdir)/Include/typeslots.h $(srcdir)/Objects/typeslots.py
-	$(PYTHON) $(srcdir)/Objects/typeslots.py < $(srcdir)/Include/typeslots.h > $(srcdir)/Objects/typeslots.inc
+Objects/typeobject.o: Objects/typeslots.inc
+Objects/typeslots.inc: $(srcdir)/Include/typeslots.h $(srcdir)/Objects/typeslots.py
+	$(PYTHON) $(srcdir)/Objects/typeslots.py < $(srcdir)/Include/typeslots.h > Objects/typeslots.inc
 
 ############################################################################
 # Header files
diff --git a/configure b/configure
index f9a62613a34..8ba3dec51fd 100755
--- a/configure
+++ b/configure
@@ -651,6 +651,8 @@ HAS_HG
 HGBRANCH
 HGTAG
 HGVERSION
+BASECPPFLAGS
+BUILDDIR
 SVNVERSION
 ARFLAGS
 AR
@@ -5205,6 +5207,24 @@ else
 	SVNVERSION="echo Unversioned directory"
 fi
 
+BUILDDIR="`pwd`"
+
+
+if test "$srcdir" != "$BUILDDIR"; then
+    # If we're building out-of-tree, we need to make sure the following
+    # resources get picked up before their $srcdir counterparts.
+    #   Objects/ -> typeslots.inc
+    #   Include/ -> Python-ast.h, graminit.h
+    #   Python/  -> importlib.h
+    # (A side effect of this is that these resources will automatically be
+    #  regenerated when building out-of-tree, regardless of whether or not
+    #  the $srcdir counterpart is up-to-date.  This is an acceptable trade
+    #  off.)
+    BASECPPFLAGS="-IObjects -IInclude -IPython"
+else
+    BASECPPFLAGS=""
+fi
+
 
 
 
diff --git a/configure.ac b/configure.ac
index 84d723aa8a7..9222c887c30 100644
--- a/configure.ac
+++ b/configure.ac
@@ -830,6 +830,24 @@ else
 	SVNVERSION="echo Unversioned directory"
 fi
 
+BUILDDIR="`pwd`"
+AC_SUBST(BUILDDIR)
+AC_SUBST(BASECPPFLAGS)
+if test "$srcdir" != "$BUILDDIR"; then
+    # If we're building out-of-tree, we need to make sure the following
+    # resources get picked up before their $srcdir counterparts.
+    #   Objects/ -> typeslots.inc
+    #   Include/ -> Python-ast.h, graminit.h
+    #   Python/  -> importlib.h
+    # (A side effect of this is that these resources will automatically be
+    #  regenerated when building out-of-tree, regardless of whether or not
+    #  the $srcdir counterpart is up-to-date.  This is an acceptable trade
+    #  off.)
+    BASECPPFLAGS="-IObjects -IInclude -IPython"
+else
+    BASECPPFLAGS=""
+fi
+
 AC_SUBST(HGVERSION)
 AC_SUBST(HGTAG)
 AC_SUBST(HGBRANCH)