diff --git a/Include/Python.h b/Include/Python.h
index 6e3303ac9a3..7260ae5cd0b 100644
--- a/Include/Python.h
+++ b/Include/Python.h
@@ -72,6 +72,7 @@
 #include "sliceobject.h"
 #include "cpython/cellobject.h"
 #include "iterobject.h"
+#include "cpython/initconfig.h"
 #include "pystate.h"
 #include "cpython/genobject.h"
 #include "descrobject.h"
@@ -83,7 +84,6 @@
 #include "cpython/pytime.h"
 #include "codecs.h"
 #include "pyerrors.h"
-#include "cpython/initconfig.h"
 #include "pythread.h"
 #include "cpython/context.h"
 #include "modsupport.h"
diff --git a/Include/cpython/pystate.h b/Include/cpython/pystate.h
index 9ac0a298baa..5adbf3b4953 100644
--- a/Include/cpython/pystate.h
+++ b/Include/cpython/pystate.h
@@ -2,8 +2,6 @@
 #  error "this header file must not be included directly"
 #endif
 
-#include "cpython/initconfig.h"
-
 PyAPI_FUNC(int) _PyInterpreterState_RequiresIDRef(PyInterpreterState *);
 PyAPI_FUNC(void) _PyInterpreterState_RequireIDRef(PyInterpreterState *, int);
 
diff --git a/Misc/NEWS.d/next/C API/2021-11-09-15-42-11.bpo-39026.sUnYWn.rst b/Misc/NEWS.d/next/C API/2021-11-09-15-42-11.bpo-39026.sUnYWn.rst
new file mode 100644
index 00000000000..77a01197921
--- /dev/null
+++ b/Misc/NEWS.d/next/C API/2021-11-09-15-42-11.bpo-39026.sUnYWn.rst	
@@ -0,0 +1,2 @@
+Fix Python.h to build C extensions with Xcode: remove a relative include
+from ``Include/cpython/pystate.h``.