diff --git a/Lib/ctypes/util.py b/Lib/ctypes/util.py
index 29bc48876ce..78f4ce31492 100644
--- a/Lib/ctypes/util.py
+++ b/Lib/ctypes/util.py
@@ -89,20 +89,22 @@ elif os.name == "posix":
         expr = r'[^\(\)\s]*lib%s\.[^\(\)\s]*' % re.escape(name)
         fdout, ccout = tempfile.mkstemp()
         os.close(fdout)
-        cmd = 'if type gcc >/dev/null 2>&1; then CC=gcc; else CC=cc; fi;' \
+        cmd = 'if type gcc >/dev/null 2>&1; then CC=gcc; elif type cc >/dev/null 2>&1; then CC=cc;else exit 10; fi;' \
               '$CC -Wl,-t -o ' + ccout + ' 2>&1 -l' + name
         try:
             f = os.popen(cmd)
             try:
                 trace = f.read()
             finally:
-                f.close()
+                rv = f.close()
         finally:
             try:
                 os.unlink(ccout)
             except OSError as e:
                 if e.errno != errno.ENOENT:
                     raise
+        if rv == 10:
+            raise OSError, 'gcc or cc command not found'
         res = re.search(expr, trace)
         if not res:
             return None
@@ -129,7 +131,13 @@ elif os.name == "posix":
             # assuming GNU binutils / ELF
             if not f:
                 return None
-            cmd = "objdump -p -j .dynamic 2>/dev/null " + f
+            cmd = 'if ! type objdump >/dev/null 2>&1; then exit 10; fi;' \
+                  "objdump -p -j .dynamic 2>/dev/null " + f
+            f = os.popen(cmd)
+            dump = f.read()
+            rv = f.close()
+            if rv == 10:
+                raise OSError, 'objdump command not found'
             f = os.popen(cmd)
             try:
                 data = f.read()
@@ -193,8 +201,32 @@ elif os.name == "posix":
                     return None
             return res.group(0)
 
+        def _findSoname_ldconfig(name):
+            import struct
+            if struct.calcsize('l') == 4:
+                machine = os.uname()[4] + '-32'
+            else:
+                machine = os.uname()[4] + '-64'
+            mach_map = {
+                'x86_64-64': 'libc6,x86-64',
+                'ppc64-64': 'libc6,64bit',
+                'sparc64-64': 'libc6,64bit',
+                's390x-64': 'libc6,64bit',
+                'ia64-64': 'libc6,IA-64',
+                }
+            abi_type = mach_map.get(machine, 'libc6')
+
+            # XXX assuming GLIBC's ldconfig (with option -p)
+            expr = r'(\S+)\s+\((%s(?:, OS ABI:[^\)]*)?)\)[^/]*(/[^\(\)\s]*lib%s\.[^\(\)\s]*)' \
+                   % (abi_type, re.escape(name))
+            res = re.search(expr,
+                            os.popen('/sbin/ldconfig -p 2>/dev/null').read())
+            if not res:
+                return None
+            return res.group(1)
+
         def find_library(name):
-            return _get_soname(_findLib_ldconfig(name) or _findLib_gcc(name))
+            return _findSoname_ldconfig(name) or _get_soname(_findLib_gcc(name))
 
 ################################################################
 # test code
diff --git a/Misc/NEWS b/Misc/NEWS
index d29fcf8ea33..2a3ae1278f2 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -236,6 +236,9 @@ Library
   support unusual filenames (such as those containing semi-colons) in
   Content-Disposition headers.
 
+- Issue #4861: ctypes.util.find_library(): Robustify. Fix library detection on
+  biarch systems. Try to rely on ldconfig only, without using objdump and gcc.
+
 Tools/Demos
 -----------