diff --git a/mk/px4_targets.mk b/mk/px4_targets.mk
index fb0a6ca97f..e3fd01a34e 100644
--- a/mk/px4_targets.mk
+++ b/mk/px4_targets.mk
@@ -122,6 +122,7 @@ px4-clean: clean CHECK_MODULES px4-archives-clean px4-cleandep
 	$(v) /bin/rm -rf $(PX4_ROOT)/src/modules/uORB/topics $(PX4_ROOT)/src/platforms/nuttx/px4_messages
 
 px4-cleandep: clean
+	$(v) mkdir -p $(PX4_ROOT)/Build
 	$(v) find $(PX4_ROOT)/Build -type f -name '*.d' | xargs rm -f
 	$(v) find $(UAVCAN_DIRECTORY) -type f -name '*.d' | xargs rm -f
 	$(v) find $(SKETCHBOOK)/$(SKETCH) -type f -name '*.d' | xargs rm -f